Enhancing bioactivity, physicochemical, and pharmacokinetic properties of a nano-sized, anti-VEGFR2 Adnectin, through PASylation technology

The crucial role of VEGF receptor 2 (VEGFR2) signaling in the angiogenesis and metastasis of solid tumors has prompted the development of inhibitors with minimal bystander effects. Recently, Adnectin C has attracted attention for cancer treatment. To overcome the problematic properties of Adnectin,...

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Detalles Bibliográficos
Autores principales: Aghaabdollahian, Safieh, Ahangari Cohan, Reza, Norouzian, Dariush, Davami, Fatemeh, Asadi Karam, Mohammad Reza, Torkashvand, Fatemeh, Vaseghi, Golnaz, Moazzami, Reza, Latif Dizaji, Sakineh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393559/
https://www.ncbi.nlm.nih.gov/pubmed/30814652
http://dx.doi.org/10.1038/s41598-019-39776-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393559/
https://www.ncbi.nlm.nih.gov/pubmed/30814652
http://dx.doi.org/10.1038/s41598-019-39776-0

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