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Genetically engineered biosynthetic pathways for nonnatural C(60) carotenoids using C(5)-elongases and C(50)-cyclases in Escherichia coli

While the majority of the natural carotenoid pigments are based on 40-carbon (C(40)) skeleton, some carotenoids from bacteria have larger C(50) skeleton, biosynthesized by attaching two isoprene units (C(5)) to both sides of the C(40) carotenoid pigment lycopene. Subsequent cyclization reactions res...

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Detalles Bibliográficos
Autores principales: Li, Ling, Furubayashi, Maiko, Wang, Shifei, Maoka, Takashi, Kawai-Noma, Shigeko, Saito, Kyoichi, Umeno, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393565/
https://www.ncbi.nlm.nih.gov/pubmed/30814614
http://dx.doi.org/10.1038/s41598-019-39289-w