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Genetically engineered biosynthetic pathways for nonnatural C(60) carotenoids using C(5)-elongases and C(50)-cyclases in Escherichia coli
While the majority of the natural carotenoid pigments are based on 40-carbon (C(40)) skeleton, some carotenoids from bacteria have larger C(50) skeleton, biosynthesized by attaching two isoprene units (C(5)) to both sides of the C(40) carotenoid pigment lycopene. Subsequent cyclization reactions res...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393565/ https://www.ncbi.nlm.nih.gov/pubmed/30814614 http://dx.doi.org/10.1038/s41598-019-39289-w |