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Detection of sub-microscopic blood levels of Plasmodium falciparum using Tandem Oligonucleotide Repeat Cascade Amplification (TORCA) assay with an attomolar detection limit

Tandem Oligonucleotide Repeat Cascade Amplification (TORCA) based on signal rather than target amplification under isothermal conditions was developed for nucleic acid assays. The initial signal was generated by hybridization of single stranded DNA targets to immobilized recognition probes followed...

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Detalles Bibliográficos
Autores principales: Ghindilis, Andrey L., Chesnokov, Olga, Ngasala, Billy, Smith, Maria W., Smith, Kenneth, Mårtensson, Andreas, Oleinikov, Andrew V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393570/
https://www.ncbi.nlm.nih.gov/pubmed/30814636
http://dx.doi.org/10.1038/s41598-019-39921-9