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Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes

The single Nrf1 gene has capability to be differentially transcripted alongside with alternative mRNA-splicing and subsequent translation through different initiation signals so as to yield distinct lengths of polypeptide isoforms. Amongst them, three of the most representatives are Nrf1α, Nrf1β and...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Qiu, Lu, Ru, Xufang, Song, Yijiang, Zhang, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393581/
https://www.ncbi.nlm.nih.gov/pubmed/30814566
http://dx.doi.org/10.1038/s41598-019-39536-0