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Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes
The single Nrf1 gene has capability to be differentially transcripted alongside with alternative mRNA-splicing and subsequent translation through different initiation signals so as to yield distinct lengths of polypeptide isoforms. Amongst them, three of the most representatives are Nrf1α, Nrf1β and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393581/ https://www.ncbi.nlm.nih.gov/pubmed/30814566 http://dx.doi.org/10.1038/s41598-019-39536-0 |