Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi

DNA polymerase theta (Polθ), a member of the DNA polymerase family A, exhibits a polymerase C-terminal domain, a central domain, and an N-terminal helicase domain. Polθ plays important roles in DNA repair via its polymerase domain, regulating genome integrity. In addition, in mammals, Polθ modulates...

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Detalles Bibliográficos
Autores principales: de Lima, Loyze P., Calderano, Simone G., da Silva, Marcelo S., de Araujo, Christiane B., Vasconcelos, Elton J. R., Iwai, Leo K., Pereira, Claudio A., Fragoso, Stenio P., Elias, M. Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393585/
https://www.ncbi.nlm.nih.gov/pubmed/30814563
http://dx.doi.org/10.1038/s41598-019-39348-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393585/
https://www.ncbi.nlm.nih.gov/pubmed/30814563
http://dx.doi.org/10.1038/s41598-019-39348-2

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