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Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi
DNA polymerase theta (Polθ), a member of the DNA polymerase family A, exhibits a polymerase C-terminal domain, a central domain, and an N-terminal helicase domain. Polθ plays important roles in DNA repair via its polymerase domain, regulating genome integrity. In addition, in mammals, Polθ modulates...
Autores principales: | de Lima, Loyze P., Calderano, Simone G., da Silva, Marcelo S., de Araujo, Christiane B., Vasconcelos, Elton J. R., Iwai, Leo K., Pereira, Claudio A., Fragoso, Stenio P., Elias, M. Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393585/ https://www.ncbi.nlm.nih.gov/pubmed/30814563 http://dx.doi.org/10.1038/s41598-019-39348-2 |
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