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Regulation of the translation activity of antigen-specific mRNA is responsible for antigen loss and tumor immune escape in a HER2-expressing tumor model

Tumor cells tend to behave differently in response to immune selective conditions. Contrary to those in therapeutic antitumor conditions, tumor cells in prophylactic antitumor conditions lose antigen expression for antitumor immune escape. Here, using a CT26/HER2 tumor model, we investigate the unde...

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Detalles Bibliográficos
Autores principales: Han, Baek-Sang, Ji, Sunhee, Woo, Sungwon, Lee, Ji Heui, Sin, Jeong-Im
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393588/
https://www.ncbi.nlm.nih.gov/pubmed/30814560
http://dx.doi.org/10.1038/s41598-019-39557-9