Cargando…
Leptin receptor deficiency induces early, transient and hyperglycaemia-independent blood-brain barrier dysfunction
Diabetes mellitus (DM) significantly increases susceptibility to central nervous system (CNS) pathologies, including stroke, vascular dementia, cognitive deficits and Alzheimer’s disease. Previous studies (mostly using the streptozotocin model) suggested that blood-brain barrier (BBB) disruption is...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393679/ https://www.ncbi.nlm.nih.gov/pubmed/30814586 http://dx.doi.org/10.1038/s41598-019-39230-1 |