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Leptin receptor deficiency induces early, transient and hyperglycaemia-independent blood-brain barrier dysfunction

Diabetes mellitus (DM) significantly increases susceptibility to central nervous system (CNS) pathologies, including stroke, vascular dementia, cognitive deficits and Alzheimer’s disease. Previous studies (mostly using the streptozotocin model) suggested that blood-brain barrier (BBB) disruption is...

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Detalles Bibliográficos
Autores principales: Corem, Noa, Anzi, Shira, Gelb, Sivan, Ben-Zvi, Ayal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393679/
https://www.ncbi.nlm.nih.gov/pubmed/30814586
http://dx.doi.org/10.1038/s41598-019-39230-1