Cargando…
Leptin receptor deficiency induces early, transient and hyperglycaemia-independent blood-brain barrier dysfunction
Diabetes mellitus (DM) significantly increases susceptibility to central nervous system (CNS) pathologies, including stroke, vascular dementia, cognitive deficits and Alzheimer’s disease. Previous studies (mostly using the streptozotocin model) suggested that blood-brain barrier (BBB) disruption is...
Autores principales: | Corem, Noa, Anzi, Shira, Gelb, Sivan, Ben-Zvi, Ayal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393679/ https://www.ncbi.nlm.nih.gov/pubmed/30814586 http://dx.doi.org/10.1038/s41598-019-39230-1 |
Ejemplares similares
-
Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood–brain barrier inducer
por: Bar, Ofri, et al.
Publicado: (2020) -
Unique features of the arterial blood–brain barrier
por: Bell, Batia, et al.
Publicado: (2023) -
Nano-scale architecture of blood-brain barrier tight-junctions
por: Sasson, Esther, et al.
Publicado: (2021) -
Transient hyperglycaemia – an underestimated problem of paediatric oncohaematology
por: Irga, Ninela, et al.
Publicado: (2012) -
P450 oxidoreductase regulates barrier maturation by mediating retinoic acid metabolism in a model of the human BBB
por: Zlotnik, Dor, et al.
Publicado: (2022)