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A regulatory variant in TBX2 promoter is related to the decreased susceptibility of congenital heart disease in the Han Chinese population

BACKGROUND: Tbx2 plays a vital role in the cardiac cushion development. In this study, we aimed to determine the relationship between common genetic variants in the promoter region of TBX2 gene and the risk of congenital heart disease (CHD). METHODS: Blood samples of 516 CHD patients and 587 control...

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Detalles Bibliográficos
Autores principales: Zhang, Ran‐ran, Cai, Ke, Liu, Lian, Yang, Qian, Zhang, Ping, Gui, Yong‐hao, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393683/
https://www.ncbi.nlm.nih.gov/pubmed/30525309
http://dx.doi.org/10.1002/mgg3.530