CdpR Inhibits CRISPR-Cas Adaptive Immunity to Lower Anti-viral Defense while Avoiding Self-Reactivity

CRISPR-Cas systems as adaptive immunity in bacteria and archaea battle against bacteriophages. However, little is known how CRISPR-Cas systems are precisely regulated to effectively eliminate intruders while not inducing self-reactivity. Here, we identify intrinsic negative modulator of CRISPR-Cas t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Ping, Pu, Qinqin, Shen, Guanwang, Li, Rongpeng, Guo, Kai, Zhou, Chuanmin, Liang, Haihua, Jiang, Jianxin, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393702/
https://www.ncbi.nlm.nih.gov/pubmed/30822746
http://dx.doi.org/10.1016/j.isci.2019.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393702/
https://www.ncbi.nlm.nih.gov/pubmed/30822746
http://dx.doi.org/10.1016/j.isci.2019.02.005

Ejemplares similares