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Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

Vascular endothelial growth factor A (VEGFA) is involved in the pathogenesis of vasoproliferative retinal diseases, such as exudative age-related macular degeneration (AMD). The objective of this study was to investigate whether dual-acting therapy based on the simultaneous expression of anti-VEGFA...

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Detalles Bibliográficos
Autores principales: Askou, Anne Louise, Alsing, Sidsel, Benckendorff, Josephine N.E., Holmgaard, Andreas, Mikkelsen, Jacob Giehm, Aagaard, Lars, Bek, Toke, Corydon, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393707/
https://www.ncbi.nlm.nih.gov/pubmed/30825671
http://dx.doi.org/10.1016/j.omtn.2019.01.012