Discovery of the Oncogenic Parp1, a Target of bcr-abl and a Potential Therapeutic, in mir-181a/PPFIA1 Signaling Pathway

miR-181a is downregulated in leukemia and affects its progression, drug resistance, and prognosis. However, the exact mechanism of its targets in leukemia, particularly in chronic myelogenous leukemia (CML), has not previously been established. Here, we use a multi-omics approach to demonstrate that...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Chunming, Liu, Yanjun, Yin, Zhao, Yang, Juhua, Huang, Guiping, Zhu, Xuejiao, Li, Yumin, Fei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393709/
https://www.ncbi.nlm.nih.gov/pubmed/30825668
http://dx.doi.org/10.1016/j.omtn.2019.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393709/
https://www.ncbi.nlm.nih.gov/pubmed/30825668
http://dx.doi.org/10.1016/j.omtn.2019.01.015

Ejemplares similares