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Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences

Recent analyses of polygenic scores have opened new discussions concerning the genetic basis and evolutionary significance of differences among populations in distributions of phenotypes. Here, we highlight limitations in research on polygenic scores, polygenic adaptation and population differences....

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Detalles Bibliográficos
Autores principales: Rosenberg, Noah A, Edge, Michael D, Pritchard, Jonathan K, Feldman, Marcus W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393779/
https://www.ncbi.nlm.nih.gov/pubmed/30838127
http://dx.doi.org/10.1093/emph/eoy036