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Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation

Oral mucositis (OM) is a common and dose-limiting side effect of cancer treatment, including 5-fluorouracil (5-FU) and radiotherapy. The efficacy of the therapeutic measures to prevent OM is limited and disease prevention is not fully observable. Amifostine is a cytoprotective agent with a described...

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Detalles Bibliográficos
Autores principales: Barbosa, S.C.M., Pereira, V.B.M., Wong, D.V.T., Santana, A.P.M., Lucetti, L.T., Carvalho, L.L., Barbosa, C.R.N., Callado, R.B., Silva, C.A.A., Lopes, C.D.H., Brito, G.A.C., Alencar, N.M.N., Lima-Júnior, R.C.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393848/
https://www.ncbi.nlm.nih.gov/pubmed/30810625
http://dx.doi.org/10.1590/1414-431X20188251