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Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation
Oral mucositis (OM) is a common and dose-limiting side effect of cancer treatment, including 5-fluorouracil (5-FU) and radiotherapy. The efficacy of the therapeutic measures to prevent OM is limited and disease prevention is not fully observable. Amifostine is a cytoprotective agent with a described...
Autores principales: | Barbosa, S.C.M., Pereira, V.B.M., Wong, D.V.T., Santana, A.P.M., Lucetti, L.T., Carvalho, L.L., Barbosa, C.R.N., Callado, R.B., Silva, C.A.A., Lopes, C.D.H., Brito, G.A.C., Alencar, N.M.N., Lima-Júnior, R.C.P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393848/ https://www.ncbi.nlm.nih.gov/pubmed/30810625 http://dx.doi.org/10.1590/1414-431X20188251 |
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