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Protective effect of dexmedetomidine against organ dysfunction in a two-hit model of hemorrhage/resuscitation and endotoxemia in rats

Dexmedetomidine (DEX), a selective agonist of α(2)-adrenergic receptors, has anti-inflammation properties and potential beneficial effects against trauma, shock, or infection. Therefore, this study aimed to investigate whether DEX might protect against multiple-organ dysfunction in a two-hit model o...

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Detalles Bibliográficos
Autores principales: Jiang, Yuanxu, Xia, Mingzhu, Huang, Qiang, Ding, Dengfeng, Li, Yali, Zhang, Zhongjun, Zhang, Xueping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393854/
https://www.ncbi.nlm.nih.gov/pubmed/30810621
http://dx.doi.org/10.1590/1414-431X20187905