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Twenty years of Mediator complex structural studies

Mediator is a large multiprotein complex conserved in all eukaryotes that plays an essential role in transcriptional regulation. Mediator comprises 25 subunits in yeast and 30 subunits in humans that form three main modules and a separable four-subunit kinase module. For nearly 20 years, because of...

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Detalles Bibliográficos
Autores principales: Verger, Alexis, Monté, Didier, Villeret, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393861/
https://www.ncbi.nlm.nih.gov/pubmed/30733343
http://dx.doi.org/10.1042/BST20180608