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The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

BACKGROUND: Of the many genetic mutations known to increase the risk of autism spectrum disorder, a large proportion cluster upon synaptic proteins. One such family of presynaptic proteins are the neurexins (NRXN), and recent genetic and mouse evidence has suggested a causative role for NRXN2 in gen...

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Detalles Bibliográficos
Autores principales: Pervolaraki, Eleftheria, Tyson, Adam L., Pibiri, Francesca, Poulter, Steven L., Reichelt, Amy C., Rodgers, R. John, Clapcote, Steven J., Lever, Colin, Andreae, Laura C., Dachtler, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394023/
https://www.ncbi.nlm.nih.gov/pubmed/30858964
http://dx.doi.org/10.1186/s13229-019-0261-9