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MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin

BACKGROUND: A large fraction of human and mouse autosomal genes are subject to random monoallelic expression (MAE), an epigenetic mechanism characterized by allele-specific gene expression that varies between clonal cell lineages. MAE is highly cell-type specific and mapping it in a large number of...

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Detalles Bibliográficos
Autores principales: Vinogradova, Svetlana, Saksena, Sachit D., Ward, Henry N., Vigneau, Sébastien, Gimelbrant, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394031/
https://www.ncbi.nlm.nih.gov/pubmed/30819107
http://dx.doi.org/10.1186/s12859-019-2679-7