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MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin
BACKGROUND: A large fraction of human and mouse autosomal genes are subject to random monoallelic expression (MAE), an epigenetic mechanism characterized by allele-specific gene expression that varies between clonal cell lineages. MAE is highly cell-type specific and mapping it in a large number of...
Autores principales: | Vinogradova, Svetlana, Saksena, Sachit D., Ward, Henry N., Vigneau, Sébastien, Gimelbrant, Alexander A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394031/ https://www.ncbi.nlm.nih.gov/pubmed/30819107 http://dx.doi.org/10.1186/s12859-019-2679-7 |
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