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Testosterone induces renal tubular epithelial cell death through the HIF-1α/BNIP3 pathway

BACKGROUND: The morbidity of nephrolithiasis is 2–3 times higher in males than in females, suggesting that androgen plays a key role in nephrolithiasis. The death of renal tubular epithelial cells (TECs) is an important pathophysiological process contributing to the development of nephrolithiasis. T...

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Detalles Bibliográficos
Autores principales: Peng, Yonghan, Fang, Ziyu, Liu, Min, Wang, Zeyu, Li, Ling, Ming, Shaoxiong, Lu, Chaoyue, Dong, Hao, Zhang, Wenhui, Wang, Qi, Shen, Rong, Xie, Fei, Zhang, Weitao, Yang, Cheng, Gao, Xiaofeng, Sun, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394048/
https://www.ncbi.nlm.nih.gov/pubmed/30819186
http://dx.doi.org/10.1186/s12967-019-1821-7