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Testosterone induces renal tubular epithelial cell death through the HIF-1α/BNIP3 pathway
BACKGROUND: The morbidity of nephrolithiasis is 2–3 times higher in males than in females, suggesting that androgen plays a key role in nephrolithiasis. The death of renal tubular epithelial cells (TECs) is an important pathophysiological process contributing to the development of nephrolithiasis. T...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394048/ https://www.ncbi.nlm.nih.gov/pubmed/30819186 http://dx.doi.org/10.1186/s12967-019-1821-7 |