Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways

The deposition of tau pathology in Alzheimer’s disease (AD) may occur first in axons of neurons and then progress back into the cell bodies to form neurofibrillary tangles, however, studies have not directly analyzed this relationship in relatively discrete circuits within the human hippocampus. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Christensen, Kyle R., Beach, Thomas G., Serrano, Geidy E., Kanaan, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394076/
https://www.ncbi.nlm.nih.gov/pubmed/30819250
http://dx.doi.org/10.1186/s40478-019-0675-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394076/
https://www.ncbi.nlm.nih.gov/pubmed/30819250
http://dx.doi.org/10.1186/s40478-019-0675-9

Ejemplares similares