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A novel TLR4 binding protein, 40S ribosomal protein S3, has potential utility as an adjuvant in a dendritic cell-based vaccine

BACKGROUND: Dendritic cells (DCs) are professional antigen presenting cells (APCs), which can activate antigen-specific CD8+ T cell immunity, resulting in tumor clearance. Immature DCs are usually stimulated by various adjuvants through their immune receptors. Among them, Toll-like receptor 4 (TLR4)...

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Detalles Bibliográficos
Autores principales: Park, Hyun Jin, Jang, Gun-Young, Kim, Young Seob, Park, Jung Hwa, Lee, Sung Eun, Vo, Manh-Cuong, Lee, Je-Jung, Han, Hee Dong, Jung, In Duk, Kang, Tae Heung, Park, Yeong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394096/
https://www.ncbi.nlm.nih.gov/pubmed/30819254
http://dx.doi.org/10.1186/s40425-019-0539-7