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The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours

BACKGROUND: Use of cyclin D1 (CCND1) gene amplification as a breast cancer biomarker has been hampered by conflicting assessments of the relationship between cyclin D1 protein levels and patient survival. Here, we aimed to clarify its prognostic and treatment predictive potential through comprehensi...

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Detalles Bibliográficos
Autores principales: Lundberg, Arian, Lindström, Linda S., Li, Jingmei, Harrell, J. Chuck, Darai-Ramqvist, Eva, Sifakis, Emmanouil G., Foukakis, Theodoros, Perou, Charles M., Czene, Kamila, Bergh, Jonas, Tobin, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394106/
https://www.ncbi.nlm.nih.gov/pubmed/30819233
http://dx.doi.org/10.1186/s13058-019-1121-4