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Optimization and Characterization of a Galleria mellonella Larval Infection Model for Virulence Studies and the Evaluation of Therapeutics Against Streptococcus pneumoniae

Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Infection is linked to high morbidity and mortality rates and antibiotic resistance within this pathogen is on the rise. Therefore, there is a need for novel antimicrobial therapies. To lower the time and costs of the drug discove...

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Detalles Bibliográficos
Autores principales: Cools, Freya, Torfs, Eveline, Aizawa, Juliana, Vanhoutte, Bieke, Maes, Louis, Caljon, Guy, Delputte, Peter, Cappoen, Davie, Cos, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394149/
https://www.ncbi.nlm.nih.gov/pubmed/30846978
http://dx.doi.org/10.3389/fmicb.2019.00311