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Optimization and Designing of Amikacin-loaded Poly D, L-Lactide-co-glycolide Nanoparticles for Effective and Sustained Drug Delivery

PURPOSE: Amikacin, a water-soluble aminoglycoside antibiotic used to treat gram-negative bacillary infections, is a Biopharmaceutics Classification System class III drug having poor permeability and short half-life. It is given parenterally, which limits its use in patients warranting “at-home care....

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Detalles Bibliográficos
Autores principales: Fatima, Saman, Panda, Amulya K., Talegaonkar, Sushma, Iqbal, Zeenat, Ahmad, Farhan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394161/
https://www.ncbi.nlm.nih.gov/pubmed/30906144
http://dx.doi.org/10.4103/jpbs.JPBS_60_18