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Human leukemia cells (HL-60) proteomic and biological signatures underpinning cryo-damage are differentially modulated by novel cryo-additives

BACKGROUND: Cryopreservation is a routinely used methodology for prolonged storage of viable cells. The use of cryo-protective agents (CPAs) such as dimethylsulfoxide (DMSO), glycerol, or trehalose is paramount to reducing cellular cryo-injury, but their effectiveness is still limited. The current s...

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Detalles Bibliográficos
Autores principales: Al-Otaibi, Noha A S, Cassoli, Juliana S, Martins-de-Souza, Daniel, Slater, Nigel K H, Rahmoune, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394207/
https://www.ncbi.nlm.nih.gov/pubmed/30535373
http://dx.doi.org/10.1093/gigascience/giy155