Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy

The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GBM). However, TMZ + RT causes excess toxicity in patients. In this study, we prepared angiopep-2 (A2) modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles for TMZ delivery (A2...

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Detalles Bibliográficos
Autores principales: Zong, Zhenkun, Hua, Lei, Wang, Zhen, Xu, Haoyue, Ye, Chengkun, Pan, Bomin, Zhao, Zongren, Zhang, Longzhen, Lu, Jun, Liu, Hongmei, Yu, Rutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394306/
https://www.ncbi.nlm.nih.gov/pubmed/30744436
http://dx.doi.org/10.1080/10717544.2018.1534897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394306/
https://www.ncbi.nlm.nih.gov/pubmed/30744436
http://dx.doi.org/10.1080/10717544.2018.1534897

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