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Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy
The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GBM). However, TMZ + RT causes excess toxicity in patients. In this study, we prepared angiopep-2 (A2) modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles for TMZ delivery (A2...
Autores principales: | Zong, Zhenkun, Hua, Lei, Wang, Zhen, Xu, Haoyue, Ye, Chengkun, Pan, Bomin, Zhao, Zongren, Zhang, Longzhen, Lu, Jun, Liu, Hongmei, Yu, Rutong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394306/ https://www.ncbi.nlm.nih.gov/pubmed/30744436 http://dx.doi.org/10.1080/10717544.2018.1534897 |
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