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MIPUP: minimum perfect unmixed phylogenies for multi-sampled tumors via branchings and ILP

MOTIVATION: Discovering the evolution of a tumor may help identify driver mutations and provide a more comprehensive view on the history of the tumor. Recent studies have tackled this problem using multiple samples sequenced from a tumor, and due to clinical implications, this has attracted great in...

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Detalles Bibliográficos
Autores principales: Husić, Edin, Li, Xinyue, Hujdurović, Ademir, Mehine, Miika, Rizzi, Romeo, Mäkinen, Veli, Milanič, Martin, Tomescu, Alexandru I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394401/
https://www.ncbi.nlm.nih.gov/pubmed/30101335
http://dx.doi.org/10.1093/bioinformatics/bty683