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MIPUP: minimum perfect unmixed phylogenies for multi-sampled tumors via branchings and ILP
MOTIVATION: Discovering the evolution of a tumor may help identify driver mutations and provide a more comprehensive view on the history of the tumor. Recent studies have tackled this problem using multiple samples sequenced from a tumor, and due to clinical implications, this has attracted great in...
Autores principales: | Husić, Edin, Li, Xinyue, Hujdurović, Ademir, Mehine, Miika, Rizzi, Romeo, Mäkinen, Veli, Milanič, Martin, Tomescu, Alexandru I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394401/ https://www.ncbi.nlm.nih.gov/pubmed/30101335 http://dx.doi.org/10.1093/bioinformatics/bty683 |
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