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Prognostic and Predictive Epigenetic Biomarkers in Oncology

Epigenetic patterns, such as DNA methylation, histone modifications, and non-coding RNAs, can be both driver factors and characteristic features of certain malignancies. Aberrant DNA methylation can lead to silencing of crucial tumor suppressor genes or upregulation of oncogene expression. Histone m...

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Detalles Bibliográficos
Autores principales: Kamińska, Katarzyna, Nalejska, Ewelina, Kubiak, Marta, Wojtysiak, Joanna, Żołna, Łukasz, Kowalewski, Janusz, Lewandowska, Marzena Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394434/
https://www.ncbi.nlm.nih.gov/pubmed/30523565
http://dx.doi.org/10.1007/s40291-018-0371-7