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AMP Kinase Activation is Selectively Disrupted in the Ventral Midbrain of Mice Deficient in Parkin or PINK1 Expression

Parkinson’s disease (PD) is a prevalent neurodegenerative movement disorder that is characterized pathologically by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of the midbrain. Despite intensive research, the etiology of PD remains poorly understood...

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Detalles Bibliográficos
Autores principales: Hang, Liting, Thundyil, John, Goh, Geraldine W. Y., Lim, Kah-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394446/
https://www.ncbi.nlm.nih.gov/pubmed/30411223
http://dx.doi.org/10.1007/s12017-018-8517-7