The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells

We have developed models of HIV latency using microglia derived from adult human patient brain cortex and transformed with the SV40 T large and hTERT antigens. Latent clones infected by HIV reporter viruses display high levels of spontaneous HIV reactivation in culture. BrainPhys, a medium highly re...

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Detalles Bibliográficos
Autores principales: Alvarez-Carbonell, David, Ye, Fengchun, Ramanath, Nirmala, Dobrowolski, Curtis, Karn, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394485/
https://www.ncbi.nlm.nih.gov/pubmed/29987742
http://dx.doi.org/10.1007/s11481-018-9798-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394485/
https://www.ncbi.nlm.nih.gov/pubmed/29987742
http://dx.doi.org/10.1007/s11481-018-9798-1

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