Increases in cytosolic Ca(2+) induce dynamin- and calcineurin-dependent internalisation of CFTR

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated, apical anion channel that regulates ion and fluid transport in many epithelia including the airways. We have previously shown that cigarette smoke (CS) exposure to airway epithelia causes a reduction in plasma membra...

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Detalles Bibliográficos
Autores principales: Patel, Waseema, Moore, Patrick J., Sassano, M. Flori, Lopes-Pacheco, Miquéias, Aleksandrov, Andrei A., Amaral, Margarida D., Tarran, Robert, Gray, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394554/
https://www.ncbi.nlm.nih.gov/pubmed/30547226
http://dx.doi.org/10.1007/s00018-018-2989-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394554/
https://www.ncbi.nlm.nih.gov/pubmed/30547226
http://dx.doi.org/10.1007/s00018-018-2989-3

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