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Increases in cytosolic Ca(2+) induce dynamin- and calcineurin-dependent internalisation of CFTR
The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated, apical anion channel that regulates ion and fluid transport in many epithelia including the airways. We have previously shown that cigarette smoke (CS) exposure to airway epithelia causes a reduction in plasma membra...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394554/ https://www.ncbi.nlm.nih.gov/pubmed/30547226 http://dx.doi.org/10.1007/s00018-018-2989-3 |