AMPK agonist AICAR ameliorates portal hypertension and liver cirrhosis via NO pathway in the BDL rat model

ABSTRACT: Recent studies have indicated that the Adenosine 5‘-monophosphate (AMP)-activated protein kinase (AMPK) pathway is closely involved in liver fibrosis and other fibrotic diseases. However, whether targeting the AMPK pathway can rescue liver fibrosis and its complications, such as portal hyp...

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Detalles Bibliográficos
Autores principales: Hu, Liangshuo, Su, Lin, Dong, Zhixia, Wu, Yunhua, Lv, Yi, George, Jacob, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394556/
https://www.ncbi.nlm.nih.gov/pubmed/30721324
http://dx.doi.org/10.1007/s00109-019-01746-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394556/
https://www.ncbi.nlm.nih.gov/pubmed/30721324
http://dx.doi.org/10.1007/s00109-019-01746-4

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