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Keeping ribosomal DNA intact: a repeating challenge

More than half of the human genome consists of repetitive sequences, with the ribosomal DNA (rDNA) representing two of the largest repeats. Repetitive rDNA sequences may form a threat to genomic integrity and cellular homeostasis due to the challenging aspects of their transcription, replication, an...

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Detalles Bibliográficos
Autores principales: Warmerdam, Daniël O., Wolthuis, Rob M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394564/
https://www.ncbi.nlm.nih.gov/pubmed/30556094
http://dx.doi.org/10.1007/s10577-018-9594-z