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Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

Hyperhomocysteinemia (HHCY) has been recognized as an independent risk factor for atherosclerosis and plays a vital role in the development of atherosclerosis. Catalpol, an iridoid glucoside extracted from the root of Rehmannia glutinosa, can produce anti-inflammatory, anti-oxidant, anti-tumor, and...

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Detalles Bibliográficos
Autores principales: Hu, Huimin, Wang, Changyuan, Jin, Yue, Meng, Qiang, Liu, Qi, Liu, Zhihao, Liu, Kexin, Liu, Xiaoyu, Sun, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394570/
https://www.ncbi.nlm.nih.gov/pubmed/30315526
http://dx.doi.org/10.1007/s10753-018-0873-9