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NLRP3/Caspase-1 Pathway-Induced Pyroptosis Mediated Cognitive Deficits in a Mouse Model of Sepsis-Associated Encephalopathy

Sepsis-associated encephalopathy (SAE) is a common complication that leads to long-term cognitive impairments and increased mortality in sepsis survivors. The mechanisms underlying this complication remain unclear and an effective intervention is lacking. Accumulating evidence suggests the nucleotid...

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Detalles Bibliográficos
Autores principales: Fu, Qun, Wu, Jing, Zhou, Xiao-Yan, Ji, Mu-Huo, Mao, Qing-Hong, Li, Qing, Zong, Man-Man, Zhou, Zhi-Qiang, Yang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394578/
https://www.ncbi.nlm.nih.gov/pubmed/30276509
http://dx.doi.org/10.1007/s10753-018-0894-4