Resistance to endocrine therapy in breast cancer: molecular mechanisms and future goals

INTRODUCTION: The majority of breast cancers (BCs) are characterized by the expression of estrogen receptor alpha (ERα+). ERα acts as ligand-dependent transcription factor for genes associated with cell survival, proliferation, and tumor growth. Thus, blocking the estrogen agonist effect on ERα is t...

Descripción completa

Detalles Bibliográficos
Autores principales: Szostakowska, Małgorzata, Trębińska-Stryjewska, Alicja, Grzybowska, Ewa Anna, Fabisiewicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394602/
https://www.ncbi.nlm.nih.gov/pubmed/30382472
http://dx.doi.org/10.1007/s10549-018-5023-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394602/
https://www.ncbi.nlm.nih.gov/pubmed/30382472
http://dx.doi.org/10.1007/s10549-018-5023-4

Ejemplares similares