Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology

Oligomers of the amyloid-β (Aβ) protein are suspected to be responsible for the development and progression of Alzheimer’s disease. Thus, the development of compounds that are able to eliminate already formed toxic Aβ oligomers is very desirable. Here, we describe the in vivo efficacy of the compoun...

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Detalles Bibliográficos
Autores principales: Schemmert, Sarah, Schartmann, Elena, Zafiu, Christian, Kass, Bettina, Hartwig, Sonja, Lehr, Stefan, Bannach, Oliver, Langen, Karl-Josef, Shah, Nadim Joni, Kutzsche, Janine, Willuweit, Antje, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394605/
https://www.ncbi.nlm.nih.gov/pubmed/30003517
http://dx.doi.org/10.1007/s12035-018-1209-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394605/
https://www.ncbi.nlm.nih.gov/pubmed/30003517
http://dx.doi.org/10.1007/s12035-018-1209-3

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