Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations

Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset, progressive neurodegenerative disorder with no known cure. Cu/Zn-superoxide dismutase (SOD1) was the first identified protein associated with familial ALS (fALS). Recently, TAR DNA-binding protein 43 (TDP-43) has been found to be a princip...

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Detalles Bibliográficos
Autores principales: Jeon, Gye Sun, Shim, Yu-Mi, Lee, Do-Yeon, Kim, Jun-Soon, Kang, MinJin, Ahn, So Hyun, Shin, Je-Young, Geum, Dongho, Hong, Yoon Ho, Sung, Jung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394608/
https://www.ncbi.nlm.nih.gov/pubmed/29982983
http://dx.doi.org/10.1007/s12035-018-1218-2

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