A Reappraisal of Sedimentation Nonideality Coefficients for the Analysis of Weak Interactions of Therapeutic Proteins

The study of weak or colloidal interactions of therapeutic proteins in different formulations allows prediction and optimization of protein stability. Various biophysical techniques have been applied to determine the second osmotic virial coefficient B(2) as it reflects on the macromolecular distanc...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Sumit K., Schuck, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394620/
https://www.ncbi.nlm.nih.gov/pubmed/30815745
http://dx.doi.org/10.1208/s12248-019-0307-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394620/
https://www.ncbi.nlm.nih.gov/pubmed/30815745
http://dx.doi.org/10.1208/s12248-019-0307-0

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