Pharmacological Sequestration of Mitochondrial Calcium Uptake Protects Neurons Against Glutamate Excitotoxicity

Neuronal excitotoxicity which is induced by exposure to excessive extracellular glutamate is shown to be involved in neuronal cell death in acute brain injury and a number of neurological diseases. High concentration of glutamate induces calcium deregulation which results in mitochondrial calcium ov...

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Detalles Bibliográficos
Autores principales: Angelova, Plamena R., Vinogradova, Darya, Neganova, Margarita E., Serkova, Tatiana P., Sokolov, Vladimir V., Bachurin, Sergey O., Shevtsova, Elena F., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394642/
https://www.ncbi.nlm.nih.gov/pubmed/30008072
http://dx.doi.org/10.1007/s12035-018-1204-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394642/
https://www.ncbi.nlm.nih.gov/pubmed/30008072
http://dx.doi.org/10.1007/s12035-018-1204-8

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