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Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment

Nonlinear mixed effects models are widely used to describe longitudinal data to improve the efficiency of drug development process or increase the understanding of the studied disease. In such settings, the appropriateness of the modeling assumptions is critical in order to draw correct conclusions...

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Detalles Bibliográficos
Autores principales: Ibrahim, Moustafa M. A., Ueckert, Sebastian, Freiberga, Svetlana, Kjellsson, Maria C., Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394649/
https://www.ncbi.nlm.nih.gov/pubmed/30815754
http://dx.doi.org/10.1208/s12248-019-0305-2