Cargando…

Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment

Nonlinear mixed effects models are widely used to describe longitudinal data to improve the efficiency of drug development process or increase the understanding of the studied disease. In such settings, the appropriateness of the modeling assumptions is critical in order to draw correct conclusions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ibrahim, Moustafa M. A., Ueckert, Sebastian, Freiberga, Svetlana, Kjellsson, Maria C., Karlsson, Mats O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394649/ https://www.ncbi.nlm.nih.gov/pubmed/30815754 http://dx.doi.org/10.1208/s12248-019-0305-2

Ejemplares similares

An Item Response Theory–Informed Strategy to Model Total Score Data from Composite Scales
por: Wellhagen, Gustaf J., et al.
Publicado: (2021)

Improved numerical stability for the bounded integer model
por: Ueckert, Sebastian, et al.
Publicado: (2020)

Variability Attribution for Automated Model Building
por: Ibrahim, Moustafa M. A., et al.
Publicado: (2019)

Performance of longitudinal item response theory models in shortened or partial assessments
por: Arrington, Leticia, et al.
Publicado: (2020)

Model‐Based Interspecies Scaling of Glucose Homeostasis
por: Alskär, Oskar, et al.
Publicado: (2017)

Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling
por: Ueckert, Sebastian, et al.
Publicado: (2014)

Study Design Selection in Early Clinical Anti‐Hyperglycemic Drug Development: A Simulation Study of Glucose Tolerance Tests
por: Ibrahim, Moustafa M. A., et al.
Publicado: (2018)

A Bounded Integer Model for Rating and Composite Scale Data
por: Wellhagen, Gustaf J., et al.
Publicado: (2019)

Modeling Composite Assessment Data Using Item Response Theory
por: Ueckert, Sebastian
Publicado: (2018)

Accelerating Monte Carlo power studies through parametric power estimation
por: Ueckert, Sebastian, et al.
Publicado: (2016)

Comparison of Power, Prognosis, and Extrapolation Properties of Four Population Pharmacodynamic Models of HbA1c for Type 2 Diabetes
por: Wellhagen, Gustaf J., et al.
Publicado: (2018)

Weight‐HbA1c‐insulin‐glucose model for describing disease progression of type 2 diabetes
por: Choy, S, et al.
Publicado: (2015)

Comparison of Precision and Accuracy of Five Methods to Analyse Total Score Data
por: Wellhagen, Gustaf J., et al.
Publicado: (2020)

Implications for Drug Characterization in Glucose Tolerance Tests Without Insulin: Simulation Study of Power and Predictions Using Model‐Based Analysis
por: Sheikh Ghadzi, SM, et al.
Publicado: (2017)

A strategy for residual error modeling incorporating scedasticity of variance and distribution shape
por: Dosne, Anne-Gaëlle, et al.
Publicado: (2015)

Impact of Obesity on Postprandial Triglyceride Contribution to Glucose Homeostasis, Assessed with a Semimechanistic Model
por: Leohr, Jennifer, et al.
Publicado: (2022)

Evidence-Based Design of Fixed-Dose Combinations: Principles and Application to Pediatric Anti-Tuberculosis Therapy
por: Svensson, Elin M., et al.
Publicado: (2017)

Linking categorical models for prediction of pleasantness score using individual predictions of sweetness and creaminess: An advancement of categorical modeling
por: Leohr, Jennifer, et al.
Publicado: (2021)

Dose-Response Mixed Models for Repeated Measures – a New Method for Assessment of Dose-Response
por: Wellhagen, Gustaf J., et al.
Publicado: (2020)

Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments
por: Chasseloup, Estelle, et al.
Publicado: (2021)

Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models
por: Ibrahim, Eman I. K., et al.
Publicado: (2023)

Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it
por: Karlsson, Markus, et al.
Publicado: (2015)

Evaluation of postprandial total triglycerides within the TIGG model for characterizing postprandial response of glucose, insulin, and GLP‐1
por: Leohr, Jennifer, et al.
Publicado: (2023)

Do working conditions contribute differently to gender gaps in self-rated health within different occupational classes? Evidence from the Swedish Level of Living Survey
por: Kjellsson, Sara
Publicado: (2021)

Longitudinal Modeling of the Relationship Between Mean Plasma Glucose and HbA1c Following Antidiabetic Treatments
por: Møller, J B, et al.
Publicado: (2013)

Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect
por: Chasseloup, Estelle, et al.
Publicado: (2023)

Automatic prediction of catalytic residues by modeling residue structural neighborhood
por: Cilia, Elisa, et al.
Publicado: (2010)

Model-based prediction of myelosuppression and recovery based on frequent neutrophil monitoring
por: Netterberg, Ida, et al.
Publicado: (2017)

Can MRI diffusion-weighted imaging identify postoperative residual/recurrent soft-tissue sarcomas?
por: ElDaly, Mai Maher, et al.
Publicado: (2018)

Weighted protein residue networks based on joint recurrences between residues
por: Karain, Wael I., et al.
Publicado: (2015)

Use of a linearization approximation facilitating stochastic model building
por: Svensson, Elin M., et al.
Publicado: (2014)

Assessment of residual body weight gain and residual intake and body weight gain as feed efficiency traits in the turkey (Meleagris gallopavo)
por: Willems, Owen W, et al.
Publicado: (2013)

Generation and application of avatars in pharmacometric modelling
por: Chasseloup, Estelle, et al.
Publicado: (2023)

Scoring Function Based on Weighted Residue Network
por: Jiao, Xiong, et al.
Publicado: (2011)

Wind Turbine Gearbox Condition Monitoring Based on Class of Support Vector Regression Models and Residual Analysis
por: Dhiman, Harsh S., et al.
Publicado: (2020)

Assessment of Phenotype Relevant Amino Acid Residues in TEM-β-Lactamases by Mathematical Modelling and Experimental Approval
por: Madzgalla, Sara, et al.
Publicado: (2021)

Modelling of mycobacterial load reveals bedaquiline’s exposure–response relationship in patients with drug-resistant TB
por: Svensson, Elin M, et al.
Publicado: (2017)

Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety
por: Minichmayr, Iris K., et al.
Publicado: (2021)

A Macaque Brain Extraction Model Based on U-Net Combined with Residual Structure
por: Wang, Qianshan, et al.
Publicado: (2022)

Methods for Predicting Diabetes Phase III Efficacy Outcome From Early Data: Superior Performance Obtained Using Longitudinal Approaches
por: Møller, JB, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4u9p3rnc28bm0tt4645oikpl2e