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Impact of erythrocytes on bacterial growth and antimicrobial activity of selected antibiotics

It has been shown that protein binding, temperature, and pH influence in vitro pharmacodynamic (PD) models. The fact that corpuscular blood compounds might also have an important impact is something which has, until now, often been neglected. We investigated if the addition of human erythrocytes to...

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Detalles Bibliográficos
Autores principales: Nussbaumer-Pröll, Alina Karoline, Knotzer, Sophie, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Jäger, Walter, Poschner, Stefan, Zeitlinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394813/
https://www.ncbi.nlm.nih.gov/pubmed/30687870
http://dx.doi.org/10.1007/s10096-018-03452-4